{"id":3372,"date":"2019-04-26T06:51:59","date_gmt":"2019-04-26T06:51:59","guid":{"rendered":"http:\/\/www.biobank.lv\/?p=3372"},"modified":"2019-12-11T10:19:44","modified_gmt":"2019-12-11T10:19:44","slug":"atklats-jauns-veids-ka-pavairot-nabassaites-asins-cilmes-sunas","status":"publish","type":"post","link":"https:\/\/www.biobank.lv\/ru\/atklats-jauns-veids-ka-pavairot-nabassaites-asins-cilmes-sunas\/","title":{"rendered":"\u041e\u0442\u043a\u0440\u044b\u0442 \u043d\u043e\u0432\u044b\u0439 \u0441\u043f\u043e\u0441\u043e\u0431 \u0440\u0430\u0437\u043c\u043d\u043e\u0436\u0435\u043d\u0438\u044f \u0441\u0442\u0432\u043e\u043b\u043e\u0432\u044b\u0445 \u043a\u043b\u0435\u0442\u043e\u043a \u043f\u0443\u043f\u043e\u0432\u0438\u043d\u043d\u043e\u0439 \u043a\u0440\u043e\u0432\u0438"},"content":{"rendered":"

Stowers medic\u012bnisko p\u0113t\u012bjumu instit\u016bt\u0101 p\u0113tnieki ir atkl\u0101ju\u0161i citu veidu, k\u0101 papla\u0161in\u0101t\/pavairot asinis veidojo\u0161\u0101s, pieaugu\u0161\u0101s cilmes \u0161\u016bnas no nabassaites asin\u012bm. P\u0113t\u012bjums palielina viena cilmes \u0161\u016bnu parauga potenci\u0101lu \u0101rst\u0113t pacientus vair\u0101kos medic\u012bniskos st\u0101vok\u013cos.<\/h3>\n

P\u0113t\u012bjuma laik\u0101 p\u0113tnieki koncentr\u0113j\u0101s uz prote\u012bnu, kas ietekm\u0113 hematopo\u0113tisko cilmes \u0161\u016bnu pa\u0161atjauno\u0161an\u0101s sp\u0113ju. Kad \u0161\u012b prote\u012bna – saukta par Ythdf2 – funkcija tika uz laiku samazin\u0101ta, p\u0113tnieki nov\u0113roja palielin\u0101tu hematopo\u0113tisko cilmes \u0161\u016bnu izple\u0161anos. Vi\u0146i ar\u012b nov\u0113roja, ka, samazinot Ythdf2, ra\u017eoto \u0161\u016bnu veids nav main\u012bjies.<\/p>\n

Pa\u0161laik cilmes \u0161\u016bnas no nabassaites asin\u012bm var tikt izmantotas, lai \u0101rst\u0113tu imunit\u0101tes trauc\u0113jumus, asins slim\u012bbas, leik\u0113miju un konkr\u0113tus v\u0113\u017ea veidus. \u0160os st\u0101vok\u013cus var \u0101rst\u0113t, ar\u012b izmantojot kaulu smadze\u0146u cilmes \u0161\u016bnas, k\u0101 ar\u012b nabassaites asinis, bet atbilsto\u0161u kaulu smadze\u0146u donoru ir gr\u016bt\u0101k atrast. Apvienotaj\u0101 Karalist\u0113 tikai 69% pacienti atrod atbilsto\u0161u kaulu smadze\u0146u donoru [1].<\/p>\n

Sal\u012bdzin\u0101\u0161anai – pieaugu\u0161as nabassaites cilmes \u0161\u016bnas nodro\u0161ina liel\u0101ku iesp\u0113ju, ka t\u0101s atbild\u012bs vair\u0101kiem cilv\u0113kiem. Tas ir t\u0101d\u0113\u013c, ka t\u0101m ir maz\u0101k sader\u012bbas pras\u012bbu nek\u0101 kaulu smadze\u0146u transplantam. Ja St<\/strong>owers instit\u016bta<\/strong> p\u0113t\u012bjums tiks turpin\u0101ts, lai \u0161\u012bs tik efekt\u012bv\u0101s cilmes \u0161\u016bnas var\u0113tu izmantot vair\u0101ku pieaugu\u0161o kond\u012bciju \u0101rst\u0113\u0161anai.<\/p>\n

Zhenrui Li, PhD, no Kanzasas medic\u012bnas centra universit\u0101tes nov\u0113roja, ka vi\u0146u p\u0113t\u012bjums pal\u012bdz\u0113ja izvair\u012bties no past\u0101v\u012bg\u0101m ar DNS saist\u012bt\u0101m mut\u0101cij\u0101m, kas var\u0113tu novest pie leik\u0113mijas vai v\u0113\u017ea \u0161\u016bnu ra\u0161an\u0101s. Tiek cer\u0113ts, ka \u0161\u012b jaun\u0101 izple\u0161anas tehnika nabassaites cilmes \u0161\u016bn\u0101m var\u0113tu tikt izmantota ar\u012b citiem pieaugu\u0161u cilmes \u0161\u016bnu veidiem.<\/p>\n

“\u0160is darbs atspogu\u013co ce\u013cu uz priek\u0161u, demonstr\u0113jot sp\u0113ju uzticami izv\u0113rst pieaugu\u0161u cilmes \u0161\u016bnu no nabassaites asin\u012bm laboratorij\u0101, gal\u012bgi nediferenc\u0113jot \u0161\u016bnas nobriedu\u0161\u0101k\u0101s un relat\u012bvi \u012bs\u0101k dz\u012bvojo\u0161\u0101s asins \u0161\u016bn\u0101s… \u0160ie atkl\u0101jumi noz\u012bm\u0113 milz\u012bgu progresu \u0161aj\u0101 jom\u0101 un tiem ir iev\u0113rojams potenci\u0101ls uzlabot t\u016bksto\u0161iem b\u0113rnu un pieaugu\u0161o rezult\u0101tus, kas piedz\u012bvo nabassaites asins transplant\u0113\u0161anu katru gadu.”<\/p>\n

Uzzi\u0146ai:
\n[1]\u00a0www.anthonynolan.org\/facts-and-stats<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Stowers medic\u012bnisko p\u0113t\u012bjumu instit\u016bt\u0101 p\u0113tnieki ir atkl\u0101ju\u0161i citu veidu, k\u0101 papla\u0161in\u0101t\/pavairot asinis veidojo\u0161\u0101s, pieaugu\u0161\u0101s cilmes \u0161\u016bnas no nabassaites asin\u012bm. P\u0113t\u012bjums palielina viena cilmes \u0161\u016bnu parauga potenci\u0101lu \u0101rst\u0113t pacientus vair\u0101kos medic\u012bniskos st\u0101vok\u013cos. P\u0113t\u012bjuma laik\u0101 p\u0113tnieki koncentr\u0113j\u0101s uz prote\u012bnu, kas ietekm\u0113 hematopo\u0113tisko cilmes \u0161\u016bnu pa\u0161atjauno\u0161an\u0101s sp\u0113ju. Kad \u0161\u012b prote\u012bna \u2013 …<\/p>","protected":false},"author":1,"featured_media":3498,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[58],"tags":[],"class_list":["post-3372","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jaunumi1"],"yoast_head":"\nNabassaites asins cilmes \u0161\u016bnas pavairo\u0161ana | Blogs | LYL BioBank Hearts<\/title>\n<meta name=\"description\" content=\"P\u0113t\u012bjums palielina cilmes \u0161\u016bnu parauga potenci\u0101lu. 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